Mechanical Ventilation from Pathophysiology to Clinical Evidence 1st edition

This book aims to give a comprehensive overview of the current challenges and solution posed to the health care professionals who need to use mechanical ventilation to treat their patients.
Mechanical ventilation is a cornerstone of the treatment of critically ill patients, as also dramatically underlined by the recent COVID-19 pandemic. The topic is not simple to approach, since it requires integration of multiple data which, in turn, result from complex interplays between patient’s condition and ventilatory settings. While technological development empowered advanced monitoring and decision support, these also increase the burden of data on the practitioners.

Furthermore, considering that sometimes mechanical ventilation is seen under two, apparently opposite, approaches, “physiology vs. protocols”, the book aims to reconcile these two aspects. And this has been done by each author following the above trajectory in their chapters.

The exposure of the topic begins from the “pathophysiology” (i.e. the “physiology of the disease”) so that the reader can better understand the concept and rationale of any given approach. At the same time, any rationale or hypothesis (for as much as supported by physiology) must hold at the proof of clinical research and evidence, which is summarized in each chapter.

In summary, the purposes is that the readers understand not only which is the best clinical practice to adopt but also why and which mechanisms this is based upon and how to approach a novel issue they might encounter. The book – addressed to physicians, nurses and respiratory therapist – features chapters on “novel” or “hot” topics like, obviously, COVID-19, ECMO, but also MV in low resource setting.

Índice Mechanical Ventilation from Pathophysiology to Clinical Evidence 1st edition

PART 1. TECHNIQUES
1. Basic physiology of respiratory system: gas exchange and respiratory mechanics Chapter 2. A short history of Mechanical Ventilation
3. Airway management in critically ill
4. Controlled mechanical ventilation: modes and monitoring
5. Assisted ventilation: pressure support and bilevel ventilation modes
6. Monitoring the patient during assisted ventilation
7. Neurally Adjusted Ventilatory Assist
8. roportional Assist Ventilation
9. Non-invasive ventilation: indications and caveats
10. High-flow Nasal Cannula
11. Nursing of mechanically ventilated and ECMO patient
12. Closed Loop ventilation modes
13. Aiway pressure release ventilation

PART 2. CLINICAL SCEARIOS
14. Acute Respiratory Failure and Acute Respiratory Distress Syndrome
15. Ventilator Induced Lung Injury and Lung Protective Ventilation
16. Mechanical ventilation in the heathy lung: OR and ICU
17. PEEP setting in ARDS
18. Ventilation in brain injured patient
19. Invaisve and noninvasive ventilation in patient with cardiac failure
20. COPD and severe asthma
21. Ventilation in the obese patient
22. Weaning the simple and complex patients
23. Noninvasive ventilation in COVID-19
24. Invasive Ventilation in COVID-19
25. Mechanical ventilation in different surgical settings
26. Following up the patients at long term
27. Mechanical Ventilation in limited resource settings
28. Mechanical Ventilation during patient’s trasferral

PART 3. ADJUNCTS TO MV
29. Prone Position
30. Veno-Venous ECMO and ECCO2R
31. Mechanical Ventilation setting during ECMO

PART 4. MONITORING
32. Ultrasound assesment of the respiratory system
33. Electrical Impedance Tomography
34. Esophageal pressure monitoring
35. Lung Volumes and volumetric capnography
36. Radiological monitoring
37. Clinical vignettes (waveforms)
38. Teaching Mechanical ventilation: on line resources and simulation

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